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Alzheimer’s disease

·July 16, 2020·5 min read

A “Feeling” for Dementia?

People with subjectively felt memory deficits also exhibited measurable cognitive deficits that were associated with abnormalities in spinal fluid.

This shows pills and a pestle and mortar

Featured Neurology

·April 2, 2019·2 min read

A “Low Dose Aspirin” for Dementia? Drug Ready for First in-Human Testing

MW-151, a new drug that blocks 'bad' inflammation in the brain is about to be tested in a new human trial. Researchers believe the new drug could help stave off dementia.

Cultured cells are shown and described in the caption.

Featured Neuroscience

·January 29, 2013·5 min read

A Better Way to Culture Central Nervous Cells

A protein associated with neuron damage in Alzheimer's patients provides a superior scaffold for growing central nervous system cells in the lab.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·October 1, 2019·3 min read

A brain protein that could put the brakes on Alzheimer’s

Reducing the expression of the protein TOM1 in mouse models of Alzheimer's disease increased the pathology, exacerbated cognitive problems, and raised levels of inflammation in the brain. Restoring TOM1 reversed the effects. Findings suggest a new therapeutic target for treating dementia.

Image shows the acetylcholine pathway in the brain.

Electrophysiology Featured Neuroscience

·January 24, 2017·2 min read

A Brain Wide Chemical Signal That Enhances Memory

Acetylcholine is released in higher amounts when the brain is engaged in more challenging mental tasks, a new study reports.

Featured Neurology

·May 11, 2017·4 min read

A Closer Look at Mild Cognitive Impairment

Study reveals 46.5% of people who were diagnosed with MCI later tested as 'normal' during a follow-up assessment.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·December 29, 2021·4 min read

A Common Risk Factor for Alzheimer’s Disease May Predispose Carriers to Severe COVID-19

Carriers of the Alzheimer's associated APOE4 gene have more than double the risk of developing severe COVID-19, a new study reports. Additionally, more microscopic hemorrhages were found in the brains of APOE4 carriers who contracted coronavirus. Researchers report those with the APOE4 gene also are more susceptible to developing long-term symptoms following COVID infection, including an increased risk of mental fatigue.

Featured Neurology Neuroscience

·May 19, 2021·6 min read

A Complex Link Between Body Mass Index and Alzheimer’s

While there is an association between obesity during midlife and an increased risk of Alzheimer's disease, researchers say the link doesn't necessarily extend into later life. A new study revealed higher genetic risk for Alzheimer's and lower BMI, especially in older men, was linked to an increased risk of Alzheimer's disease and predicted the disease progression.

oligodendrocytes from alzheimer's brain tissue are shown

Featured Genetics Neurology Neuroscience

·May 1, 2019·6 min read

A comprehensive map of how Alzheimer’s affects the brain

Axon myelination is significantly disrupted in patients with Alzheimer's disease. Researchers also found brain cells of men and women vary significantly in how their genes respond to the neurodegenerative disease.