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bipolar disorder

Electrophysiology Featured Neuroscience Psychology

·February 19, 2020·5 min read

Altered potassium levels in neurons may cause mood swings in bipolar disorder

Increased potassium currents were responsible for hyperactivity of CA3 neurons. When exposed to potassium channel blockers, the hyperactivity disappeared. However, when exposed to lithium, the drug not only reversed hyperactivity but reduced potassium currents at the same time. The findings strengthen the case that potassium currents play a role in bipolar disorder.

Autism Featured Neuroscience Open Neuroscience Articles Psychology

·March 20, 2018·3 min read

Amygdala Neurons Increase as Children Become Adults; Except in Autism

A new PNAS study reveals typically developing children experience neurogenesis in the amygdala as they become adults. However, for those with autism, the amygdala loses neurons as they age.

Featured Psychology

·July 21, 2018·7 min read

Beef Jerky and Other Processed Meats Associated with Manic Episodes

A new study reports eating processed meats could contribute to mania associated with bipolar disorder. Researchers found people who had been hospitalized for mania were 3.5 times more likely to have eaten cured meats prior to admittance.

Featured Neurology Neuroscience Psychology

·January 4, 2017·3 min read

Bipolar Disorder and Epilepsy Linked to Turning Down an Inhibitory Switch in Brain Circuits

A new study looks at how a gene associated with bipolar disorder affects the balance between inhibition and excitation; revealing a link with epilepsy.

Featured Neuroscience Psychology

·October 25, 2023·7 min read

Bipolar Disorder Can Be Detected With Blood Test

A novel approach combines an online psychiatric assessment with a blood test to diagnose bipolar disorder, a condition often misdiagnosed as major depressive disorder. This blood test, alongside the digital assessment, can accurately diagnose up to 30% of bipolar disorder cases.

Image shows the location of the striatum in the brain.

Featured Psychology

·July 8, 2016·4 min read

Bipolar Disorder Linked to Unexpected Region of Brain

According to researchers, genes within the striatum could be deeply involved in bipolar disorder.

This shows the outline of a person sitting slumped on a chair

Featured Neurology Neuroscience Psychology

·May 23, 2019·4 min read

Bipolar disorder may be linked to Parkinson’s disease

People with bipolar disorder have higher incidences of Parkinson's disease than those without the psychiatric condition. Manic and depressive episodes were associated with an elevated risk of developing Parkinson's disease.

This shows the outline of a person with the brain and pancreas highlighted.

Featured Genetics Neuroscience Psychology

·August 16, 2025·5 min read

Bipolar Mood Shifts Linked to Insulin Signaling in the Pancreas

A new study uncovers a pancreas–hippocampus feedback loop that may help explain mood swings in bipolar disorder. Using patient-derived pancreatic islets, researchers found reduced insulin secretion linked to elevated RORβ, a bipolar risk gene.

Featured Neuroscience Psychology

·August 7, 2017·5 min read

Brain Acidity Imbalance in Psychiatric Disorders

Researchers discover imbalanced pH and lactate levels in the brains of mouse models of schizophrenia, ASD and bipolar disorder. They believe the imbalances could reflect an underlying pathophysiology to some psychiatric disorders.

This shows a young woman looking out of a window

Featured Neuroscience Open Neuroscience Articles Psychology

·June 11, 2019·3 min read

Brain activation provides individual-level prediction of bipolar disorder risk

Combining neuroimaging data with machine learning, researchers have identified patterns of brain activation during reward anticipation, associated with an increased risk of developing bipolar disorder. The patterns of neural activation predict the severity of mania symptoms in young adults who have not yet developed the disorder.

Featured Neuroscience Psychology

·July 8, 2024·5 min read

Brain Area Linked to Mood Swings in Bipolar Disorder

A new study identifies brain areas linked to mood swings and pleasure response in bipolar disorder. Researchers found that people with bipolar disorder show heightened activity in the ventral striatum during rewards, explaining extreme mood shifts. Reduced communication between the ventral striatum and anterior insula may contribute to these mood changes. These findings could lead to better treatments for managing bipolar disorder.

Featured Psychology

·February 2, 2017·4 min read

Brain Circuits May Reveal Which Young People Are Likely to Commit Suicide

Researchers find significant differences in the brains of teens with bipolar disorder that attempt to take their lives over those with the disorder who have never attempted suicide.

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bipolar disorder

Altered potassium levels in neurons may cause mood swings in bipolar disorder

Amygdala Neurons Increase as Children Become Adults; Except in Autism

Beef Jerky and Other Processed Meats Associated with Manic Episodes

Bipolar Disorder and Epilepsy Linked to Turning Down an Inhibitory Switch in Brain Circuits

Bipolar Disorder Can Be Detected With Blood Test

Bipolar Disorder Linked to Unexpected Region of Brain

Bipolar disorder may be linked to Parkinson’s disease

Bipolar Mood Shifts Linked to Insulin Signaling in the Pancreas

Brain Acidity Imbalance in Psychiatric Disorders

Brain activation provides individual-level prediction of bipolar disorder risk

Brain Area Linked to Mood Swings in Bipolar Disorder

Brain Circuits May Reveal Which Young People Are Likely to Commit Suicide

Teenage Cannabis Use Linked to 52% Higher Schizophrenia Risk

Physical Activity Rewires the Traumatized Brain

Gene Linking Schizophrenia to Decision-Making Found

Positive Childhood Experiences and Special Health Care Needs

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