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Fragile X Syndrome

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·February 18, 2026·9 min read

Mapping Technology Reveals the Brain’s Secret Protein Factories

DNA is just the beginning. A new mapping technology reveals that brain cells produce proteins at wildly different rates, providing a missing link in our understanding of neurological disease.

Autism Featured Neuroscience

·June 25, 2024·4 min read

CBD and Metformin Show Promise for Autism Disorders

Cannabidiol (CBD) and metformin can alleviate behavioral difficulties in mouse models of Fragile X and Phelan-McDermid syndromes. Both conditions, linked to autism spectrum disorder, saw improvements in speech, social interactions, and repetitive behaviors. This promising study paves the way for potential new treatments with minimal side effects. Ongoing clinical trials aim to confirm these findings in humans.

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Autism Featured Genetics Neuroscience

·May 19, 2023·4 min read

Potential New Treatment for a Leading Cause of Autism

Researchers have identified a potential new treatment method for Fragile X Syndrome (FXS), a leading cause of autism spectrum disorders. The method involves contracting the CGG trinucleotide repeat in the FMR1 gene, thereby restoring the essential FMRP protein expression necessary for brain development.

Autism Featured Genetics Neuroscience

·February 16, 2023·4 min read

Sensory Signals Are Integrated Differently, Underrepresented by Neurons in Autism

Environmental sensory signals are integrated differently in those with Fragile X syndrome, causing them to be underrepresented by cortical pyramidal neurons.

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Autism Featured Genetics Neuroscience

·December 13, 2021·5 min read

New Hope for People Living With a Genetic Cause of Autism

Gene editing may provide hope for the treatment of Fragile X, the leading genetic cause of autism.

Autism Featured Genetics Neuroscience

·December 16, 2020·3 min read

New Insights Into Fragile X Syndrome and the Fetal Brain

Researchers have identified a potential molecular mechanism that causes Fragile X syndrome in the developing fetal brain.

Featured Genetics Open Neuroscience Articles Psychology

·June 24, 2020·4 min read

Unexpected mental illnesses found in a spectrum of a rare genetic disorder

Fragile X syndrome patients with prematuration had a much earlier onset of neurological problems, including earlier symptoms of neurodegeneration. They also experienced emotional processing problems. Some of the most common emotional processing disorders reported were mood regulation, anxiety, and psychosis.

Featured Genetics Neuroscience

·February 17, 2020·2 min read

Disease-causing repeats help human neurons function

Study reports repeats in genes associated with Fragile X syndrome normally regulate how and when proteins are made in neurons.

Featured Neuroscience Psychology

·January 16, 2020·3 min read

Sleep linked to language skills in neurodevelopmental disorders

Sleep disruptions are common features of Fragile X syndrome, Williams syndrome, and Down syndrome. The disruption of sleep in these neurodevelopmental disorders appears to be linked to language development. The longer children with neurodevelopmental disorders slept, the more words they knew.

Autism Featured Neuroscience Open Neuroscience Articles

·July 23, 2019·3 min read

Study looks at stem cells for answers to how a type of autism develops

Stem cell study reveals a genetic defect associated with fragile X syndrome delays the production of neurons during a critical stage of embryonic development.

Autism Featured Neuroscience

·May 29, 2019·2 min read

Early statin treatment may help children with Fragile X

Lovastatin, a common statin usually prescribed to control cholesterol, corrected learning and memory deficits associated with Fragile X syndrome in rodent models.